A series of unexplained deaths in foreign hospitals sends Jennifer Hernandez, an idealistic UCLA medical student, on a desperate search for answers about her grandmother's sudden death. With the discovery of other unexplained deaths followed by hasty cremations, Jennifer reaches out to her mentor, New York City medical examiner Dr. Laurie Montgomery, who has her own deep connection to Jennifer's grandmother.

Taking a year off from her medical studies and leaving New York City, Pia Grazdani accepts a job at Nano, a nanotechnology institute, where she is quickly warned not to investigate the other work done at the facility and not to ask questions about their source of funding.

"After Dr. Jack Stapleton's near-death confrontation with a medical serial killer, his wife, NYC Chief Medical Examiner Laurie Montgomery, is carrying the load both at home and at work. When Laurie insists Dr. Ryan Sullivan--an underperforming senior pathology resident who is spending his required month at the medical examiner's office but who truly detests doing forensic autopsies--assist her on a suicide autopsy in the hopes of stimulating his interest...