Two years after a horrible incident made them run away, vampire princess Lissa and her guardian-in-training Rose are found and returned to St. Vladimir's Academy, where one focuses on mastering magic, the other on physical training, while both try to avoid the perils of gossip, cliques, gruesome pranks, and sinister plots.

While on a school skiing trip, guardian-in-training Rose faces everything from misunderstandings between friends to fights among factions of Moroi as reports of horrific Strigoi attacks raise tensions, ultimately leading Rose and some of those closest to her into a battle that teaches her much about life, death, and love.

Struggling to maintain a boundary between her Alchemist teachings and the urgings of her heart, Sydney meets Marcus Finch, who pushes her to rebel, while Sydney's encounter with an evil magic user compels her to embrace her inner magic.

When alchemist Sydney is ordered into hiding to protect the life of Moroi princess Jill Dragomir, the last place she expects to be sent is a human private school in Palm Springs, California. But at their new school, the drama is only just beginning.